Sildenafil Treats Antidepressant Sexual Side Effects

Study offers an answer to people taking newer antidepressants:

People experiencing antidepressant-associated erectile dysfunction might find hope in a very study of the drug Sildenafil (Viagra). In a six-week, randomized study of 90 men with sexual unwanted side effects from antidepressants, 54.5% of these addressed with Sildenafil showed improvement, based on the January 1, 2003 issue from the Journal in the American Medical Association (JAMA).

The participants inside study were 90 men receiving treatment for major depressive disorder (MDD) with serotonin reuptake inhibitor (SRI) antidepressants at considered one of three outpatient medical centers within the United States. To be within the study, the men were required to take remission from depression in addition to be experiencing sexual dysfunction from the treatment with SRI antidepressants. Researchers used criteria in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) to define antidepressant-associated impotence (AASD). Participants in the study were required to be experiencing impotence caused by at least one with the following: erectile dysfunction (ED); inability to come with an orgasm; and/or ejaculatory delay with a minimum of 10 minutes.

The antidepressants taken by participants within the study were the SRI antidepressants: citalopram (Celexa), clomipramine (Anafranil), fluoxetine (Prozac), fluvoxamine (Luvox), imipramine (Tofranil), nefazodone (Serzone), paroxetine (Paxil), sertraline (Zoloft), and venlafaxine (Effexor). The researchers mention that 30% to 70% of men and women taking these SRIs (mainly for depressive and panic disorders) experience sexual unwanted effects, and nearly 90% of those with sexual unwanted side effects will eradicate treatment while using antidepressants because of this. Clearly, อ่านโดจินแปลไทย for these negative effects are essential for successful treatment with SRIs to continue.

The study lasted for 6 weeks. Of the 90 participants, 45 received 50 mg of Sildenafil (Viagra) and 45 received a placebo. Participants were told to consider one pill around an hour before sexual activity but just weren’t take more than one pill daily.
The results with the study show Sildenafil (Viagra) to become promising option for the many people experiencing antidepressant sexual unwanted effects. Using several questionnaires to measure results, researchers found that 54.5% of participants taking Sildenafil were “much or very much improved” as compared to 4.4% of those using the placebo. Although Sildenafil (Viagra) is approved by the Food and Drug Administration (FDA) to deal with impotence problems, researchers found out that participants experiencing other sorts of impotence also showed improvement. Additionally, researchers found that patients remained in remission from depression while taking Sildenafil, showing that treatment wouldn’t normally interfere while using depression treatment.